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Oxytocin serves a vital role in sexual reproduction, especially during the stimulation of the nipples and clitoris. Oxytocin also serves a necessary role in orgasms, which explains why its depletion often negatively affects a female’s response to stimulation. Too much masturbation can ruin a women’s response to stimulation and lead to female orgasm dysfunction. Women who no longer feel stimulation during sex may want to take all-natural herbs and supplements.